Study Finds No Difference in Long-Term Outcomes Between Minimally Invasive and Open Discectomies

Current evidence does not support the routine use of minimally invasive surgery to remove herniated disc material pressing on the nerve root or spinal cord in the neck or lower back, a study has concluded.

The study, published in CMAJ Open, was led by Nathan Evaniew, research fellow in orthopedics and a Ph.D., student in health research methodologies at McMaster University’s Michael G. DeGroote School of Medicine in Hamilton, Ontario.

In comparing it with open surgery, the researchers found that while minimally invasive surgery for cervical or lumbar discectomy may speed up recovery and reduce post-operative pain, it does not improve long-term function or reduce long-term extremity pain. Minimally invasive surgery for discectomy also requires advanced technical expertise and may be associated with increased risks of neurologic injury, incidental damage to the outer covering of the brain and spinal cord, and further surgery.

“Surgeons already perform open discectomies through relatively small incisions. Selecting the right patients and providing technically adequate nerve-root decompression are probably the most important determinants of long-term outcomes,” said Evaniew. “We were not surprised to find that outcomes are essentially the same between minimally invasive and open discectomies.” For carefully selected patients who fail to improve with nonsurgical management, conventional open discectomy surgery often provides good or excellent results, the authors indicated.

Evaniew and colleagues performed a meta-analysis of previous studies to examine the effects of minimally invasive versus open surgery on functional outcomes, pain, complications and reoperations among patients undergoing cervical or lumbar discectomy. They searched the MEDLINE, Embase and Cochrane Library databases for reports of relevant randomised controlled trials and reviewed four trials involving 431 patients in the cervical discectomy group, and 10 trials involving 1,159 patients in the lumbar discectomy group.

“Many spinal surgery procedures are known to have difficult learning curves, and surgeons embarking on minimally invasive surgical techniques should obtain specialised training to minimize complications,” the authors wrote. “Conventional open techniques for spinal surgery are themselves technically demanding, and minimally invasive techniques are likely even more challenging.”

In addition to concluding that current research evidence does not support the routine use of minimally invasive surgery for cervical or lumbar discectomy, the researchers also found an overall lack of high-quality research, which suggests further well-designed trials are needed.